ODQ 是一種選擇性可溶性的鳥苷酰環(huán)化酶抑制劑，可增強(qiáng)順鉑促人間皮瘤細(xì)胞凋亡的作用。

產(chǎn)品性質(zhì)：

Cas No.:41443-28-1

別名:1H-[1,2,4]惡草靈并[4,3-A]喹喔啉-1-酮

化學(xué)名:1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one

Canonical SMILES:O=C1ON=C2N1C3=CC=CC=C3N=C2

分子式:C9H5N3O2

分子量:187.16

溶解度:DMF: 30 mg/ml,DMF:PBS (pH 7.2) (1:1): .1 mg/ml,DMSO: 15 mg/ml,Ethanol: .5 mg/ml

儲存條件:Store at -20°C

注意事項(xiàng)：

為了您的安全和健康，請穿實(shí)驗(yàn)服并戴一次性手套操作。

References:

1. Garthwaite J, Southam E, Boulton CL, Nielsen EB, Schmidt K, Mayer B. Potent and selective inhibition of nitric oxide-sensitive guanylyl cyclase by 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one. Mol Pharmacol. 1995 Aug;48(2):184-8. PubMed PMID: 7544433.

2. Schrammel A, Behrends S, Schmidt K, Koesling D, Mayer B. Characterization of 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one as a heme-site inhibitor of nitric oxide-sensitive guanylyl cyclase. Mol Pharmacol. 1996 Jul;50(1):1-5. PubMed PMID: 8700100.