The MemGlow? product line consists of bright & non toxic live cell membrane probes. Originally developed as the MEMBRIGHT? probes1-3, MemGlow? fluorogenic probes exhibit ideal microscopy characteristics including high specificity, low background, and simple application. MemGlow? 640 has been validated with multiple microscopy techniques including epifluorescent (widefield), confocal, 2-photon, and TIRF1. MemGlow?  has been confirmed to work in fixed cells, fixed tissue, live cells, and other phospholipid membranes such as extracellular vesicles including exosomes1-3.

Features and advantages of MemGlow? probes:

Bright and fluorogenic

Simple staining protocol and low working concentration

Compatible with live and fixed cell staining (see important technical notes in About Tab)

Compatible with ex vivo and fixed tissue staining 

Non-toxic probes permit long-term imaging and re-imaging of live cells

Efficient labeling of filopodia and nanotubes at nanomolar concentrations

No dye quenching steps required

Do not alter sample biology

Utilize cyanine or BODIPY dyes with zwitterionic membrane anchor groups

Superior to many existing plasma membrane dyes

For more detailed information on using this product see the About Tab 

2 nmol of MemGlow will produce a 20μM stock solution when reconstituted with 100 μl of anhydrous DMSO